About NMN and NAD
NMN is a substance the body uses to make NAD, which plays a role in cellular metabolism. Studies have examined both infusions and oral intake in people. What can be learned depends on the participants, methods and study duration. This page explains findings from early research and their limitations.
Infusion method and approximate visit schedule
The clinic offers NMN by infusion, with about 1 visit per month. The actual amount, interval and number of sessions depend on your health and assessment. A vial is a container unit and does not indicate the amount of active ingredient. Doses and methods used in research do not establish the clinic's treatment conditions.
What to tell the physician
Tell us your goals, current health, medicines and care at other medical facilities. Consider the fees, limits of the evidence and uncertainty about effects.
What research on NMN infusions shows
NMN is a substance the body uses to make NAD, which plays a role in cellular metabolism. Its role in the body and the health effects of administering it are separate questions.
In 2022, an exploratory study gave 10 healthy adults 1 intravenous dose of NMN and examined blood tests and other measures for up to 5 hours. It reported an increase in blood NAD and no acute abnormalities in the measures observed. The study was small and brief, with no control group. It did not establish safety with repeated or long-term use, reversal of ageing, longer life or disease prevention.
Early research on oral NMN includes a study of a single dose in 10 healthy men. Oral intake and infusion enter the body differently. Oral study results cannot directly establish the effects or safety of infusions. The studies in the table do not specify the product or dose used at the clinic.
Scroll the table horizontally to view all columns.
| Study | Participants and method | What this study cannot tell you on its own |
|---|---|---|
| 2022 exploratory study of a single intravenous dose | 10 healthy adults. Tests and other measures observed for up to 5 hours after administration. | Safety of repeated or long-term use, reversal of ageing and disease prevention |
| 2020 early study of a single oral dose | 10 healthy men. Safety and changes in the body were observed after oral intake. | Effects or safety of administering NMN by infusion |
These are examples of published original studies. The table does not specify the clinic's product, dose or interval and is not a comprehensive review of NMN research.
Precautions and risks
Risks of the infusion procedure include pain at the needle site, bruising, vein irritation or inflammation and infection. These should be considered separately from side effects of the NMN product itself. Small, short studies cannot establish safety with repeated or long-term use. Tell staff if you feel unwell or notice pain or swelling.
This is an overview. Please consider a treatment or test after receiving an explanation specific to your care.
Fees and conditions
- NMN additional 1 vial for course patients (reference price)
- ¥66,000 (including tax)
- NMN, 1 vial per session × 10 sessions
- ¥627,000 (including tax)
- NMN, 2 vials per session × 10 sessions
- ¥1,232,000 (including tax)
- NMN, 3 vials per session × 10 sessions
- ¥1,815,000 (including tax)
Standalone infusions are unavailable. ¥66,000 including tax is a reference price for an additional 1 vial for course patients. A vial is a container unit and does not indicate the amount of active ingredient. Confirm any additional fees such as the initial consultation, your dose and interval, and the course conditions before treatment. The listed fees apply to NMN only.
What to check before your consultation
- What has been found in studies involving people?
- What is the approval status and how is the product sourced?
- What are my options if I choose not to have it?
Write down your questions and bring them with your medication record and previous test results.
Ask about NMNReference information
- The University of Tokyo Hospital study of oral NMN in humans
- Kimura and colleagues' 2022 study of a single intravenous dose of NMN (English)
- Irie and colleagues' 2020 study of a single oral dose of NMN (English)
- Northampton General Hospital patient information on intravenous cannulas (English)
- NHS information on phlebitis (English)
Products, amounts and methods used in studies do not identify what the clinic uses or the conditions of individual treatments.